Tolerance of the chest-to-back accelerations (+Gx) at the peak value of 6.7 g was evaluated in two Soyuz crew members during the ballistic landing after an off-nominal launch. The G-tolerance of crew member 1 (CM1) when passing through the dense layers of the atmosphere was assessed as good based on analysis of reported subjective sensations and results of objective physiological investigations: the physiological reactions of the body to the action of g-force were of a moderate nature; no critical signs limiting G-tolerance were noted. The G-tolerance of crew member 2 (CM2) was assessed based on analysis of objective physiological information only, which allowed us to consider it good. CM1 highly appreciated the experience gained during flight preparation, including the experience of centrifuge (CF) spins, which enabled him to act professionally in an emergency situation. The tolerance of g-force with a maximum value of 6.7 units by the ISS crew after the off-nominal Soyuz launch was assessed as good.