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Treviño, Ana; Aguilera, Antonio; Caballero, Estrella; Benito, Rafael; Parra, Patricia; Eiros, Jose M; Hernandez, Araceli; Calderón, Enrique; Rodríguez, Manuel; Torres, Alvaro; García, Juan; Ramos, Jose Manuel; Roc, Lourdes; Marcaida, Goitzane; Rodríguez, Carmen; Trigo, Matilde; Gomez, Cesar; de Lejarazu, Raul Ortíz; de Mendoza, Carmen; Soriano, Vincent
Virology journal, 03/2012, Letnik: 9, Številka: 1Journal Article
Although most HTLV infections in Spain have been found in native intravenous drug users carrying HTLV-2, the large immigration flows from Latin America and Sub-Saharan Africa in recent years may have changed the prevalence and distribution of HTLV-1 and HTLV-2 infections, and hypothetically open the opportunity for introducing HTLV-3 or HTLV-4 in Spain. To assess the current seroprevalence of HTLV infection in Spain a national multicenter, cross-sectional, study was conducted in June 2009. A total of 6,460 consecutive outpatients attending 16 hospitals were examined. Overall, 12% were immigrants, and their main origin was Latin America (4.9%), Africa (3.6%) and other European countries (2.8%). Nine individuals were seroreactive for HTLV antibodies (overall prevalence, 0.14%). Evidence of HTLV-1 infection was confirmed by Western blot in 4 subjects (prevalence 0.06%) while HTLV-2 infection was found in 5 (prevalence 0.08%). Infection with HTLV types 1, 2, 3 and 4 was discarded by Western blot and specific PCR assays in another two specimens initially reactive in the enzyme immunoassay. All but one HTLV-1 cases were Latin-Americans while all persons with HTLV-2 infection were native Spaniards. The overall prevalence of HTLV infections in Spain remains low, with no evidence of HTLV-3 or HTLV-4 infections so far.
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in: SICRIS
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