Protecting from solar radiation remains a very stimulating field of research and development. Improvement of performances of UV/IR radiation shielding devices is thus constantly pursued. With increase of computer strength and code efficiency, simulation becomes a real asset in this investigation. In this study, we report an efficient multiscale simulation protocol to design and optimize such photonic devices based on polymers. The simulation approach combines atomistic-level techniques, i.e. classical molecular mechanics, and linear scaling-DFT in order to get full description of the optical properties of polymers over a large wavelength range. At each step of the procedure, validation with experimental data is carried out, confirming the accuracy of the approach. The resulting optical constants enable designing of a multilayer photonic heterostructure purposely optimized for UV/NIR-radiations protection. The ensuing simulated device reveals very promising optical performance. It exhibits a transparency higher than 90% in the visible range and shows high UV absorptance. Moreover, a strong NIR-shielding ability of 96% is achieved. Display omitted •A protocol to design and optimize polymers-based photonic devices is proposed.•The approach combines atomistic-level techniques and device-level simulation.•The ensuing simulated device reveals very promising optical performance.•Transparency higher than 90% and high UV absorptance are achieved.•A strong NIR-shielding ability of 96% is obtained.