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  • Standardizing double-blind,...
    Sampson, Hugh A., MD; Gerth van Wijk, Roy, MD; Bindslev-Jensen, Carsten, MD, PhD; Sicherer, Scott, MD; Teuber, Suzanne S., MD; Burks, A. Wesley, MD; Dubois, Anthony E.J., MD; Beyer, Kirsten, MD; Eigenmann, Philippe A., MD; Spergel, Jonathan M., MD, PhD; Werfel, Thomas, MD; Chinchilli, Vernon M., PhD

    Journal of allergy and clinical immunology, 12/2012, Letnik: 130, Številka: 6
    Journal Article, Conference Proceeding

    In an article reviewing the status of gastrointestinal allergy in the New England Journal of Medicine in 1949, Ingelfinger et al1 decried the reliance on patients' "incrimination" of specific foods, outcome of trial diets, or association of abdominal complaints with symptoms believed to be allergic in making the diagnosis of food allergy. Recently, the National Institutes of Health-sponsored expert panel "Guidelines for the diagnosis and management of food allergy," reaffirmed the utility of the DBPCFC for diagnosing food allergy after an extensive review of the current literature.11 However, the expert panel noted that open or single-blind challenges could also be acceptable when the challenge outcome is negative or when objective symptoms are elicited that exactly recapitulate the history of the reaction.