At present, psychological barriers are widespread in physical education, and all physical education teachers need to solve this issue. The emergence of wireless communication networks and new interactive devices have a significant influence on multimodal human–computer interaction, which has become a prominent area of research. In this paper, we analyze the psychological obstacles in sports by leveraging mobile intelligent information systems (MIIS) within the wireless communication networks. The paper begins by introducing the reasons and background of sports psychological barriers, then examines and summarizes existing academic research on sports psychological barriers and mobile intelligent information systems. Subsequently, the paper presents a comprehensive summary in conjunction with computer vision’ multimodal learning for human–computer interaction. Furthermore, an algorithm is proposed, and various algorithms are analyzed for sports’ psychological barriers within the framework of mobile intelligent information systems. The paper also includes a factor analysis of sports psychological obstacles within the mobile intelligent information system. Finally, various experiments are conducted and the results are summarized and discussed. The experimental findings indicate a 4% improvement in the effectiveness of using mobile intelligent information systems for addressing sports psychological disorders compared to traditional methods. The utilization of multimodal human interaction extends to diverse domains of learning and daily life. Leveraging multimodal interaction technology and virtual reality technology in developing new interactive applications holds the potential to enhance the convenience and naturalness of human–computer interaction.