The retreating behavior of glaciers observed in most of the Hindu Kush–Karakoram–Himalaya (HKH) region has given rise to the formation and expansion of numerous glacial lakes in the region. The lakes expansion under changing climate usually poses high risk of glacial lake outburst flood (GLOF) hazard for the downstream communities. In the present study, the risk of glacial lake outburst flood was investigated in the HKH region of Pakistan using LANDSAT-8 OLI (Operational Land Imager) image data of 2013 period coupled with ground information. The results of present study revealed 3044 lakes (surface area about 134.8 km 2 ) in the three HKH ranges, maximum in the Karakoram (1325) and minimum in the Hindu Kush range (722) during 2013. The lakes exhibited an overall increase of about 26% in number and 7% in area in the region during 2001–2013 period. The increase in lake number was 91% within 2500–3500 m, 20% within 3500–4500 m and 31% within 4500–5500 m elevation range. Among total identified lakes during 2013, 36 were characterized as potentially dangerous glacial lakes (PDGLs) that can pose GLOF hazard in the HKH region. A regular monitoring of cryosphere changes and critical glacial lakes is essential to develop sustainable risk management strategies for this region in future.