nationalresearchcollaborative@gmail.com van Schalkwyk and colleagues discuss the health effects of a no deal Brexit.1 After the United Kingdom’s referendum on European Union (EU) membership, medical students and postgraduate trainees from across Europe made a commitment to continue to support pan-European research collaboration.23 International collaboration enables rapid completion of large, high quality studies, producing broadly generalisable data that inform improvements to patient care.4 Now the UK has left the EU, it is meaningful to see studies being published by student and trainee driven European collaboratives.56 These studies have been delivered by actively engaging thousands of students and trainees across Europe to work together for the benefit of patients. Signatories: Riaz A Agha (Academic Surgery Collaborative); Rory J Piper, Angelos Kolias, Aimun Jamjoom (British Neurosurgical Trainee Research Collaborative); Veeru Kasivisvanathan (British Urology Researchers in Surgical Training); Ruth Blanco-Colino, Alessandro Sgrò (European Student Research Collaborative); Carly Welch, Lauren McCluskey (Geriatric Medicine Research Collaborative); Ewen Harrison (GlobalSurg Collaborative); Francesco Pata, Gianluca Pellino (Italian Surgical Research Group); Sarantos Kaptanis (London Surgical Research Group); Joana Simoes, António Sampaio Soares (Portuguese Surgical Research Collaborative); George Ramsay, Michael Wilson (Scottish Surgical Research Group); Natalie Blencowe (Severn and Peninsula Audit and Research Collaborative for Surgeons); Richard Wilkin (Single Use Negative pRessure dressing for Reduction In Surgical site infection following Emergency laparotomy); Kenneth A McLean, Sivesh K Kamarajah, Emily C Mills (Student Audit and Research in Surgery Collaborative); Niall Brindl, Julia Gsenger, Charlotte Kuner, Marius Schwab (Student-Initiated German Medical Audit); Rhianon Reynolds (Welsh Ophthalmic Research Collaborative); James Glasbey, Richard Evans, Dmitri Nepogodiev (West Midlands Research Collaborative); Joshua Burke, Peter Coe (White Rose Surgical Collaborative). Evaluation of appendicitis risk prediction models in adults with suspected appendicitis.