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Moody, Catherine L.; Franckevičius, Vilius; Drouhin, Pauline; Klein, Johannes E.M.N.; Taylor, Richard J.K.
Tetrahedron letters, 04/2012, Letnik: 53, Številka: 15Journal Article
A practical and efficient entry to spirocyclic oxindoles from readily accessible anilide precursors, using only catalytic amounts of an inexpensive copper salt together with air as the sole re-oxidant, is described. In addition to providing access to a broad range of spiro-oxindole products, the utility of this method is demonstrated in a formal synthesis of the natural product, horsfiline.
