This paper provides an analysis of Andrija Štampar’s activities after World War II on the establishment of effective international health. Analyzed archival materials have confirmed with numerous evidence that Štampar as the president of the Interim Commission of the World Health Organization (WHO) played a crucial role in the establishment of the ideological starting points and organization of the WHO system, which remain relevant to date. Apart from the strategic foundations, it has been shown that his principles regarding the need for practical action based on the best professional knowledge and experience have no alternatives. The above is presented in the paper with the details of Štampar’s activities during the cholera epidemic in Egypt and associated with the experiences of the recent global crisis caused by the COVID pandemic. Rad donosi pregled aktivnosti Andrije Štampara nakon Drugoga svjetskog rata i opisuje zatečeno stanje neaktivnih nacionalnih zdravstvenih organizacija. Obrađenom arhivskom građom brojnim je dokazima utvrđeno kako je upravo Andrija Štampar, kao predsjednik tzv. Prijelazne komisije Svjetske zdravstvene organizacije (SZO), tadašnjim intenzivnim djelovanjem presudno djelovao na uspostavu ideoloških polazišta i organizacije sustava SZO, koji ostaju aktualni do danas. Osim strateških osnova, pokazalo se da njegova načela potrebe praktičnog djelovanja utemeljenog na najboljim znanjima i iskustvima struke nemaju alternative. To je u radu ilustrirano detaljima Štamparova globalnog djelovanja tijekom epidemije kolere u Egiptu i povezano s iskustvima nedavne globalne krize uzrokovane COVID pandemijom.