E-viri
Recenzirano
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Kamimura, Hiroteru; Watanabe, Jun; Sugano, Tomoyuki; Kohisa, Junji; Abe, Hiroyuki; Kamimura, Kenya; Tsuchiya, Atsunori; Takamura, Masaaki; Okoshi, Shogo; Tanabe, Yoshinari; Takagi, Ritsuo; Nonaka, Hirofumi; Terai, Shuji
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, March 2021, 2021-Mar, 2021-03-00, 20210301, Letnik: 27, Številka: 3Journal Article
Although hepatitis B virus infection is well-described, the additional risk posed by oral bleeding in individuals with chronic hepatitis B virus infection has not been determined. This study aimed to determine the quantity of hepatitis B virus in the saliva of carriers in Japan, as a means of understanding the potential risk for horizontal transmission. Saliva samples from 48 confirmed hepatitis B virus carriers were included in the analysis. Hepatitis B virus concentrations and the presence of occult blood as periodontal disease were evaluated in each sample. Hepatitis B surface antigen was identified in 46 of the 48 samples (98%), with hepatitis B virus DNA identified in 19 of the 48 saliva samples (40%). Occult blood was detected in 32 (67%) samples with the prevalence increasing as a function of age (r = 0.413; P = 0.003). There was a significantly positive correlation between hepatitis B virus DNA levels in the serum and saliva specimens (r = 0.895; P < 0.001). Occult blood in saliva was detected in most participants. The detection of hepatitis B virus DNA correlated positively with hepatitis B virus in the serum and occult blood in the saliva. Therefore, improved care of periodontal disease among older people is important for preventing horizontal transmission of hepatitis B virus.
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Vir: Osebne bibliografije
in: SICRIS
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