Herein, we investigate the effect of various solvents on the extraction of natural dyes from two different fruit skins, namely Annona atemoya (Atemoya) and Physalis peruviana (Physalis), as photosensitizers for dye-sensitized solar cells (DSSCs). The functional groups of the extracted dye pigmentation were confirmed using Fourier-transform infrared spectroscopy (FTIR) to verify the presence of anthocyanin radicals. To fabricate the DSSCs, semiconducting TiO2 nanoparticles were deposited on FTO glass as a photoanode (using the spin-coating method), and platinum was also deposited on FTO glass as a photocathode (using the drop-casting method). Atomic force microscopy (AFM) and scanning electron microscopy (SEM) were performed to verify the surface roughness and morphologies of the TiO2 photoanode and Pt photocathode. The photoelectric performance results of the fabricated DSSCs were examined and revealed the influence of various solvents on the extraction of Annona atemoya and Physalis peruviana dyes. The extraction of Annona atemoya and Physalis peruviana dyes in methanol solvent showed higher energy conversion efficiency of 2.02 % and 0.31 %, respectively, compared to other solvent extractions. In general, this work demonstrates that constructing solar cells from natural dyes at a reduced cost is a viable and sustainable alternative to traditional silicon cells. •Annona atemoya and Physalis peruviana fruits as used novel light harvesters in DSSCs.•Influence of different solvent extraction of pigments in DSCCs performance.•Improvement of extraction of natural pigments in methanol as solvent.•Annona atemoya fruit peel containing to be rich in Acetogenins.•Physalis peruviana fruits peel containing to be rich in oleanolic acid and betulin.