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  • Simultaneous preparation of...
    Römer, J.; Füchtner, F.; Steinbach, J.; Kasch, H.

    Journal of labelled compounds & radiopharmaceuticals, September 2001, Letnik: 44, Številka: 10
    Journal Article

    After successfully synthesizing 16α‐18Ffluoroestradiol‐3,17β‐disulphamate in an automatic procedure, we studied the conditions for obtaining 16α‐18Ffluoroestradiol‐monosulphamates in a similar manner. The described procedure can simultaneously provide approximately 3 GBq of 16α‐18Ffluoroestradiol‐3‐sulphamate and 1 GBq of 16α‐18Ffluoroestradiol‐17β‐sulphamate of high radiochemical purity. By treating 16α‐18Ffluoroestradiol‐3,17β‐disulphamate with Kryptofix 2.2.2 and potassium carbonate, 16α‐18Ffluoroestradiol‐17β‐sulphamate also becomes available at high radioactivity. Copyright © 2001 John Wiley & Sons, Ltd.