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Suan, Dan; Sundling, Christopher; Brink, Robert
Current opinion in immunology, 04/2017, Letnik: 45Journal Article
Highlights • Only high-affinity GC B cells undergo PC differentiation. • PC differentiation initiates in the light zone via antigen contact. • Maturing PCs requires T-cell help and egress through the DZ. • MBC differentiation is predominantly restricted to low affinity GC B cells. • MBC differentiation also initiates in the light zone.
