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  • Oxidative stress and mitoch...
    Chrysostomou, Vicki; Rezania, Fatemeh; Trounce, Ian A; Crowston, Jonathan G

    Current opinion in pharmacology, 02/2013, Letnik: 13, Številka: 1
    Journal Article

    Graphical abstract Highlights ► Oxidative stress is thought to contribute to the pathogenesis of glaucoma. ► Mitochondria are a central source and target of oxidative stress. ► Signs of oxidative stress and damage are present in glaucomatous tissue. ► Reactive oxygen species can cause retinal ganglion cell death directly or indirectly. ► Mitochondrial antioxidants may improve disease outcomes in glaucoma.