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Li, Tingyou; Tsuda, Yuko; Minoura, Katsuhiko; In, Yasuko; Ishida, Toshimasa; Lazarus, Lawrence H.; Okada, Yoshio
Chemical & Pharmaceutical Bulletin, 06/2006, Letnik: 54, Številka: 6Journal Article
Six phenylalanine analogues containing 2′-methyl-, 2′,6′-dimethyl-, 2′-ethyl-6′-methyl-, 2′-isopropyl-6′-methyl-, 2′,4′,6′-trimethyl-, and 3′,5′-dimethyl-L-phenylalanine were synthesized enantioselectively through asymmetric hydrogenation of acetamidoacrylate derivatives. Enzymatic digestion and X-ray analysis supported the L-configuration of the phenylalanine derivatives obtained.
