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van Dievoet, Marie-Astrid; Brusa, Davide; Octave, Marie; Horman, Sandrine; Stephenne, Xavier
Platelets (Edinburgh), 10/2022, Letnik: 33, Številka: 7Journal Article
The platelet transmembrane receptor GPVI can be assessed together with other platelet membrane markers in a whole blood multicolor flow cytometry panel. The advantage of combining multiple antibodies in a single tube is the possibility of distinguishing multiple platelet subgroups. In this short communication, we describe an activation problem encountered with anti-GPVI, clone HY101. Activation of platelets was seen after the addition of anti-GPVI in a flow cytometry panel, highlighted by the expression of the activation markers CD62P, PAC-1, CD63, and CD107a. This was also confirmed by platelet aggregation studies.
