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Recenzirano
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Ghorra, Camille; Pommier, Romain; Piveteau, Arthur; Rubbia-Brandt, Laura; Vilgrain, Valérie; Terraz, Sylvain; Ronot, Maxime
European radiology, 04/2021, Letnik: 31, Številka: 4Journal Article
Objectives To compare the performance of standard and simulated short gadoxetic acid-enhanced MRI protocols for the detection of colorectal liver metastases (CRLM). Methods From 2008 to 2017, 67 patients (44 men (66%); mean age 65 ± 11 years old) who underwent gadoxetic acid-enhanced MRI during the initial work-up for colorectal cancer were included. Exams were independently reviewed by two readers blinded to clinical data in two reading sessions: (1) all acquired sequences (standard “long” protocol) and (2) only T2-weighted, diffusion-weighted, and hepatobiliary phase images (simulated “short” protocol). Readers characterized detected lesions using a 5-point scale (1—certainly benign to 5—certainly malignant). A lesion was considered a CRLM when the score was ≥ 3. The reference standard was histopathology or 12-month imaging follow-up. Chi-square, Student’s t , and McNemar tests were used for comparisons. Results A total of 486 lesions including 331 metastases (68%) were analyzed. The metastasis detection rate was 86.1% (95% CI 82–89.4)–86.7% (82.6–90) and 85.8% (81.6–89.2)–87% (82.9–90.2) with the short and long protocols, respectively ( p > 0.99). Among detected lesions, 92.1% (89.1–94.4)–94.8% (92.2–96.6) and 84.6% (80.8–87.7)–88.8% (85.4–91.5) were correctly classified with the short and long protocols, respectively ( p = 0.13 and p = 0.10). The results remained unchanged when lesions scored ≥ 4 were considered as CRLM. Conclusion The diagnostic performance of a simulated short gadoxetic enhanced-MR protocol including T2-weighted, diffusion-weighted, and hepatobiliary phase appears similar to that of a standard long protocol including dynamic phase images. Since this protocol shortens the duration of MR examination, it could facilitate the evaluation of patients with colorectal liver metastases. Key Points • The detection rate of colorectal metastases with a simulated, short, MRI protocol was similar to that of a standard protocol. • The performance of both protocols for the differentiation of metastases and benign lesions appears to be similar. • A short MR imaging protocol could facilitate the evaluation of patients with colorectal liver metastases.
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Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Vir: Osebne bibliografije
in: SICRIS
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