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Zubrzak, P; Kociołek, K; Smoluch, M; Silberring, J; Kowalski, M L; Szkudlińska, B; Zabrocki, J
Acta biochimica polonica, 01/2001, Letnik: 48, Številka: 4Journal Article
Linear and cyclic hymenistatin I (HS I) analogues with dipeptide segments Ile2-Pro3 Pro3-Pro4 and Val6-Pro7 replaced by their tetrazole analogues Ile2-psiCN4-Ala3', Pro3-psiCN4-Ala4 and Val6-psiCN4-Ala7 were synthesized by the solid phase peptide synthesis method and cyclized with the TBTU and/or HATU reagent. The peptides were examined for their immunosuppressive activity in the lymphocyte proliferation test (LPT).
