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Azibi, M; Draguet-Brughmans, M; Bouche, R; Tinant, B; Germain, G; Declercq, J P; Van Meerssche, M
Journal of pharmaceutical sciences, March 1983, Letnik: 72, Številka: 3Journal Article
A second polymorph of spiperone, 8-3-(p-fluorobenzoyl)-propyl-1-phenyl-1,3,8-triazaspiro4,5 decan-4-one, has been isolated and characterized by thermal analysis and IR spectrometry. Its structure was solved by X-ray diffraction analysis. The results are compared with those previously obtained on spiperone, the main difference being in the conformation of the side chain and in the nature of the hydrogen bonding.
