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  • Serum Cytokine Profiles of ...
    Ohji, Goh; Funakoshi, Yohei; Ebisawa, Kei; Yakushijin, Kimikazu; Arakawa, Yu; Saegusa, Jun; Kawamoto, Shinichiro; Imanishi, Takamitsu; Mori, Yasuko; Iwata, Kentaro; Minami, Hironobu

    Kobe journal of the medical sciences, 2021, Letnik: 67, Številka: 2
    Journal Article

    COVID-19 patients reveal various clinical manifestations; however, the specific mechanisms and factors contributing to rapid recovery remain unclear. We performed serum cytokine profiling using a bead-based immunoassay in six COVID-19 patients with mild symptoms who experienced rapid recovery. All patients had fever that resolved within 4 days. During the study, the interferon gamma-related protein 10 (IP-10) level rapidly increased initially, and then rapidly decreased in all six patients. Similarly, the interferon (IFN)-λ2/3 levels rapidly increased initially, and then decreased in five of the six patients. IP-10 and IFN-λ2/3 may play a key role in the rapid recovery of mild COVID-19.