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Kolho, K L; Turner, D; Veereman-Wauters, G; Sladek, M; de Ridder, L; Shaoul, R; Paerregaard, A; Amil Dias, J; Koletzko, S; Nuti, F; Bujanover, Y; Staiano, A; Bochenek, K; Finnby, L; Levine, A; Veres, G
Journal of pediatric gastroenterology and nutrition, 2012-October, Letnik: 55, Številka: 4Journal Article
Assessment of fecal calprotectin, a surrogate marker of mucosal inflammation, is a promising means to monitor therapeutic response in pediatric inflammatory bowel disease, especially if the result is readily available. We tested the performance of a novel calprotectin rapid test, Quantum Blue, versus the conventional enzyme-linked immunosorbent assay in 134 stool samples from 56 pediatric patients with Crohn disease. The intraclass correlation coefficient analysis reflected good agreement (intraclass correlation coefficient 0.97 95% confidence interval 0.95-0.98) but agreement was better in lower values, where dilutions were not required. Using a cutoff of 100 μg/g for normal values, the percentage agreement between the 2 tests was 87%. The optimal cutoff values to guide clinical decisions in the therapy of inflammatory bowel disease have yet to be determined.
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Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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in: SICRIS
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