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Palaniappan, Krishnan K.; Ramirez, R. Matthew; Bajaj, Vikram S.; Wemmer, David E.; Pines, Alexander; Francis, Matthew B.
Angewandte Chemie (International ed.), April 26, 2013, Letnik: 52, Številka: 18Journal Article
NMR imaging: Filamentous fd bacteriophage expressing antibodies recognizing the epidermal growth factor receptor (EGFR) were modified to incorporate cage‐like xenon‐binding molecules (CryA). The resulting contrast agent was shown to bind to an EGFR‐positive cell line and detected by hyperpolarized 129Xe NMR spectroscopy using chemical exchange saturation transfer (hyperCEST, see picture).
