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Epplein, Meira; McCall, Shannon J.; Wang, Frances; Alagesan, Priya; Brown, HannahSofia; Wawrzynski, Joseph; Labriola, Caroline; Zuzul, Rachel; Cook, Christian; Dillon, Melanie; Hyslop, Terry; Patierno, Steven R.; Salama, Nina R.; Garman, Katherine S.
Clinical and translational gastroenterology, 06/2024, Letnik: 15, Številka: 6Journal Article
INTRODUCTION: We designed a race-conscious study to assess the presence of Helicobacter pylori v irulence factor cagA in a retrospective cohort of patients with active H. pylori infection. METHODS: We compared cagA status by race in gastric tissue samples from 473 patients diagnosed with active H. pylori infection from 2015 to 2019. RESULTS: H. pylori + Black patients were 2 times more likely to be cagA + than H. pylori + White patients (82% vs 36%, P < .0001). DISCUSSION: Presence of cagA is common among endoscopy patients with active H. pylori infection; appropriate testing and treatment of H. pylori can both reduce gastric cancer risk and address health disparities.
