The contribution analysis the effects of digital transformation, provides a critical assessment of the policies on e-government in Europe and in Italy, and draft a research agenda focused on Liguria Region. The article moves from the need to conduct research aimed at analyzing the change in the relations between subject and institution in contemporary western societies. The article, focusing on official documents, explores the strategies of digital transformation adopted by the EU. Liguria is a case study of interest because, starting from the 2016-2018 Digital Strategic Program, has adopted a strong focus on the principles of Open Government and an explicit decision to invest in specific digital services for citizens and businesses.