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Huang, Wei; Liu, Da-Wei; Wang, Guang-Jian; Zhang, Hong-Min; Zhou, Gao-Sheng; Liu, Jing-Jing; Wang, Xiao-Ting
Chinese medical journal, 07/2021, Letnik: 134, Številka: 14Journal Article
...the identification of biomarker, which could inform the clinical diagnosis of autophagic impairment, will be essential for guiding the management of septic patients. Additionally, a higher serum level of LC3β was associated with significantly lower levels of IL-1β and IL-18 Figure 1B. ...there was no significant difference observed with regard to the identified pathogens (gram-negative vs. gram-positive) (median and interquartile interval; 253.83, 219.99–300.80 vs. 297.32, 240.24–392.12 pg/mL, P = 0.055). ...there may be bias in patient selection. ...the use of LC3β to monitor the progression of sepsis or response to treatment interventions requires further investigation.
