Correlates of immune protection in HIV-1 infection: what we know, what we don't know, what we should know

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Correlates of immune protection in HIV-1 infection: what we know, what we don't know, what we should know

Pantaleo, Giuseppe; Koup, Richard A

Nature medicine, 200408, 2004-Aug, 2004-8-00, 20040801, Letnik: 10, Številka: 8

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The field of vaccinology began in ignorance of how protection was instilled in vaccine recipients. Today, a greater knowledge of immunology allows us to better understand what is being stimulated by various vaccines that leads to their protective effects: that is, their correlates of protection. Here we describe what is known about the correlates of protection for existing vaccines against a range of different viral diseases and discuss the correlates of protection against disease during natural infection with HIV-1. We will also discuss why it is important to design phase 3 clinical trials of HIV vaccines to determine the correlates of protection for each individual vaccine.

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Pantaleo, Giuseppe | Koup, Richard A

Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.

Leto	Faktor vpliva		Izdaja		Kategorija		Razvrstitev
Leto	JCR	SNIP	JCR	SNIP	JCR	SNIP	JCR	SNIP

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