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Roche, Christopher D; Brereton, Russell J L; Ashton, Anthony W; Jackson, Christopher; Gentile, Carmine
European journal of cardio-thoracic surgery, 09/2020, Letnik: 58, Številka: 3Journal Article
Abstract Summary Previous attempts in cardiac bioengineering have failed to provide tissues for cardiac regeneration. Recent advances in 3-dimensional bioprinting technology using prevascularized myocardial microtissues as ‘bioink’ have provided a promising way forward. This review guides the reader to understand why myocardial tissue engineering is difficult to achieve and how revascularization and contractile function could be restored in 3-dimensional bioprinted heart tissue using patient-derived stem cells.
