•A novel RGO/WO3-nanohybrids were synthesized by a facile hydrothermal method.•The bandgap was found to be reduced from 2.80 to 2.32 eV with the incorporation of RGO into WO3 matrix.•The WRG-40 nanocomposite exhibited high mineralization ability for RhB and CIP degradation.•The maximum photocatalytic activity of RhB (96%) and CIP (90%) was observed by WRG-40 composite. Display omitted This proposed work suggests the fabrication of hybrid WO3/reduced graphene oxide (WRG) composites with rod-like structures through the facile hydrothermal method. The WO3 nanorod has been grown on the GO sheet, concurrent reduction of GO has been made, and the as-prepared WRG is employed as photocatalyst. The fabricated samples structural and morphological properties were scrutinized by X-ray diffraction (XRD) and Field Emission Scanning Electron Microscope (FESEM). The chemical composition and surface binding energy were monitored by using X-ray photoelectron spectroscopy (XPS). The WRG composites exhibited excellent photocatalytic activity for decomposing organic dye Rhodamine B (RhB) & antibiotic pollutants like Ciprofloxacin (CIP) under visible light irradiation. The adequate loading of GO on WO3 matrix reduced the charge carrier's recombination and enhanced the degradation performance. Hybrid photocatalyst exhibit higher rate constant values; 2.76 × 10−2 min−1 and 2.07 × 10−2 min−1 for RhB and CIP pollutants, respectively.