Quality management and metrology play an important and basic role in individual activities of different function enterprises in Multi-functions Integrated Factory MFIF to ensure the realisation of such systems. MFIF is an innovative concept and a new model for future enterprises which has been developed to meet the demands for cost-effective customer-driven design and manufacturing, to realise agile and optimal manufacturing production. In this paper, the intelligent quality assurance system and metrology in MFIF is outlined. Especially the off-line programming technique for intelligent co-ordinate measurement technique ICMT as basis for simultaneous quality assurance is described and an intelligent measuring cell for quality assurance, data collection and data evaluation in MFIF is proposed and discussed.