Sustainable Development Goal 12 and target 12.3 set by the United Nations aims to reduce”food waste” per capita global for 50% losses by 2030. Databases such as the PhInd could help us to achieve set goals via mapping the potential ways for valorization of polyphenols from the agri-food by-products and waste. Fruit by-products (73.2% of the PhInd entries) are the most studied sources of polyphenols and future studies might be more focused on vegetables. More than half (55.8%) of entries were evaluated polyphenols in samples created in laboratory. These samples could have significantly different composition from industrial samples. Solid-liquid extraction (53.5%) and solvents like water, ethanol and aqueous ethanol (51.5%) were the most often used for extraction of polyphenols. Green solvents as NADES (0.4%) are rarely used in studies and should be more explored. •Fruit by-products and waste are 73.2% of PhInd entries•Data for waste from other plant classes (vegetables, nut, cereals) are lacking•Samples from industrial setting should be used more (44% entries) for valorization•Extraction of polyphenols with NADES (only 0.4%) needs further elaboration