In fluid dynamics, the Clebsch transformation allows for the construction of a first integral of the equations of motion leading to a self-adjoint form of the equations. A remarkable feature is the description of the vorticity by means of only two potential fields fulfilling simple transport equations. Despite useful applications in fluid dynamics and other physical disciplines as well, the classical Clebsch transformation has ever been restricted to inviscid flow. In the present paper a novel, generalized Clebsch transformation is developed which also covers the case of incompressible viscous flow. The resulting field equations are discussed briefly and solved for a flow example. Perspectives for a further extension of the method as well as perspectives towards the development of new solution strategies are presented. •A generalized Clebsch transformation is established applying to viscous flow.•The resulting 5 equations are a first integral of Navier–Stokes-equations.•An axisymmetric stagnation flow against a solid wall is considered as flow example.•Perspectives of the method for other problems, e.g. in solid mechanics are discussed.