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Richardson, Timothy I.; Frank, Scott A.; Wang, Minmin; Clarke, Christian A.; Jones, Scott A.; Ying, Bai-Ping; Kohlman, Dan T.; Wallace, Owen B.; Shepherd, Timothy A.; Dally, Robert D.; Palkowitz, Alan D.; Geiser, Andrew G.; Bryant, Henry U.; Henck, Judith W.; Cohen, Ilene R.; Rudmann, Daniel G.; McCann, Denis J.; Coutant, David E.; Oldham, Samuel W.; Hummel, Conrad W.; Fong, Kin C.; Hinklin, Ronald; Lewis, George; Tian, Hongqi; Dodge, Jeffrey A.
Bioorganic & medicinal chemistry letters, 07/2007, Letnik: 17, Številka: 13Journal Article
SAR studies are described, which led to the discovery of novel SERMs for the treatment of uterine fibroids. Structure–activity relationship studies are described, which led to the discovery of novel selective estrogen receptor modulators (SERMs) for the potential treatment of uterine fibroids. The SAR studies focused on limiting brain exposure and were guided by computational properties. Compounds with limited impact on the HPO axis were selected using serum estrogen levels as a biomarker for ovarian stimulation.
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Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Vir: Osebne bibliografije
in: SICRIS
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