Imunoenzimska ELISA metoda (engl. Enzyme-Linked ImmunoSorbent Assay) se istražuje u posljednje vrijeme kao brza, jednostavna i visokospecifična analitička metoda za unaprjeđenje i standardizaciju kvalitete meda i pčelinjih proizvoda. Med i pčelinji proizvodi se osim zbog nutritivne vrijednosti učestalo koriste i zbog brojnih pozitivnih bioloških učinaka, a ELISA metoda svoju primjenu u standardizaciji njihove kvalitete može pronaći kod utvrđivanja autentičnosti, botaničkog podrijetla te razlikovanja uzoraka prirodnog meda. Metoda se razvija u svrhu određivanja pčelinjih proteina i peptida, kao što su apalbumin-1 i defensin-1, a koji mogu predstavljati biljege izvornosti. Imunoenzimska ELISA metoda primjenu pronalazi i u određivanju peludi određene biljne vrste u svrhu utvrđivanja botaničkog podrijetla, te pri procjeni kvalitete određivanjem enzima, kao i u svrhu razlikovanja uzoraka prirodnog meda određivanjem specifičnih proteina. The Enzyme-Linked ImmunoSorbent Assay (ELISA) has recently been investigated as a fast, simple and highly specific analytical method for improving and standardisation of the quality of honey and bee products. Apart from their nutritive value, honey and bee products are often used due to their numerous positive biological effects, and the ELISA method can find its application in standardisation of their quality through determination of authenticity, botanical origin, and distinguishing natural honey samples. The method is being developed for the purpose of determination of beederived proteins and peptides, such as apalbumin-1 and defensin-1, which may be markers of botanical origin. Immunoenzyme ELISA method is also used in determination of pollen of certain plant species for the purpose of determination of botanical origin, and in assessment of quality by determination of enzymes, as well as for the purpose of distinguishing natural honey samples by determination of specific proteins.