A general method for asymmetric synthesis of heteroaryl‐containing cycles via palladium‐catalyzed cyclization is reported. Most classes of nitrogen‐containing aromatics, including pyridines, quinolines, pyrimidines, various azoles and the derivatives of nucleobases are compatible substrates, offering various heteroaryl‐substituted cyclopentane, pyrrolidine, furanidine and bicyclo4.3.1decadiene derivatives with good to excellent enantioselectivity and diastereoselectivity. A general method for asymmetric synthesis of heteroaryl‐containing compounds provides different nitrogen‐containing aromatics, including pyridines quinolines, pyrimidines, various azoles and the derivatives of nucleobases with good to excellent enantioselectivity and diastereoselectivity. This new method is expected to serve as a useful tool in the discovery of new therapeutics and agrochemicals.