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  • Translocation (2;3)(p21;q26...
    Herens, Christian; Hermanne, Jean-Philippe; Tassin, Francoise; Fassotte, Marie France; Thiry, Albert; Jamar, Mauricette; Schaaf-Lafontaine, Nicole; Fillet, Georges; Koulischer, Lucien

    Cancer genetics and cytogenetics, 04/1999, Letnik: 110, Številka: 1
    Journal Article, Web Resource

    Translocation t(2p;3q) is a rare but recurrent finding in myeloid disorders. We present the first case of primary myelofibrosis with t(2;3)(p21;q26) as the sole chromosomal anomaly. The comparison with the 11 other previously published myeloid-associated t(2p;3q) cases confirms that this nonrandom translocation involves a pluripotent stem cell and is associated with a poor prognosis.