E-viri
PDF
Recenzirano
Odprti dostop
-
Coulson, A; Levy, A; Gossell-Williams, M
West Indian medical journal, 2014, Letnik: 63, Številka: 6Journal Article
Rituximab was the first chemotherapeutic monoclonal antibody (CmAb) approved for clinical use in cancer therapeutics in 1997 and has significantly improved the clinical outcomes in non-Hodgkin's lymphoma. Since then, numerous CmAbs have been developed and approved for the treatment of various haematologic and solid human cancers. In this review, the classification, efficacy and significantly reduced toxicity of CmAbs available for use in the United States of America are presented. Finally, the limitations of CmAbs and future considerations are explored.
