An overview of the design and application of coupled solid‐phase extraction‐capillary electrophoresis (SPE‐CE) systems reported in the literature between July 2013 and June 2015 is provided in this paper. The present article is a continuation of our previous review papers on this topic which covered the time period 2000–2013 (Electrophoresis 2008, 29, 108–128; Electrophoresis 2010, 31, 44–54; Electrophoresis 2012, 33, 243–250; Electrophoresis 2014, 35, 128–137). The use of in‐line and on‐line SPE‐CE approaches is treated and outlined in this review. Recent advancements, such as, for example, the use of aptamers as affinity material for in‐line SPE‐CE, the use of a bead string design for in‐line fritless SPE‐CE, and new interfacing techniques for the on‐line coupling of SPE to CE, are outlined. Selected examples demonstrate the applicability of the coupled SPE‐CE systems for biomedical, pharmaceutical, environmental, and food studies. A complete overview of the recent SPE‐CE studies is given in table format, providing information on sample type, SPE sorbent, coupling mode, detection mode, and LOD. Finally, some general conclusions and perspectives are provided.