E-viri
Recenzirano
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Patel, Seema, Dr
Biomedicine & pharmacotherapy, 12/2016, Letnik: 84Journal Article
Highlights • Cardiac glycosides such as digitoxin, digoxin, ouabain, oleandrin are used for heart ailment treatment since ages. • Lack of information on proper dosage and specificity has led to accidental poisoning and mortality. • These glycosides have been validated to have anticancer roles. • The biological mechanism has been identified as Na-K-ATPase pump manipulation and regulation of renin-angiotensin axis. • This review discusses the latest findings in this area and suggests testable hypotheses for better exploitation of these glycosides in healthcare.
