Global developmental delay (GDD) is a chronic neurological disturbance that includes defects in one or more developmental domains. Although some diagnosed delays are benign, certain presentations are more worrisome. The developmental domains can be motor, cognitive, daily activities, speech or language, and social or personal development. The etiology of GDD can be prenatal, perinatal, or postnatal. It can be diagnosed early in childhood as the delay or absence of one or more developmental milestones. Hence the role of pediatric dentists and pediatricians becomes more crucial in identifying this condition. Thimmegowda U, Chikkanarasaiah N, P A, Global Developmental Delay in Children with Full Mouth Rehabilitation: A Case Series. Int J Clin Pediatr Dent 2023;16(3):522-527.