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Covey, Dan P; Roitman, Mitchell F; Garris, Paul A
Trends in neurosciences, 04/2014, Letnik: 37, Številka: 4Journal Article
Highlights • Natural rewards reinforce behavior by eliciting phasic increases in dopamine (DA transients). • Abused drugs pharmacologically evoke DA transients and thus mimic natural rewards. • We propose a reclassification of addictive DA transporter inhibitors (DAT-Is). • Reclassification based on their ability to elicit DA transients via DA cell bursting. • This bursting could be basis for initial reinforcement of drug-seeking/-taking.
