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Bruning, A.H.L; Aatola, H; Toivola, H; Ikonen, N; Savolainen-Kopra, C; Blomqvist, S; Pajkrt, D; Wolthers, K.C; Koskinen, J.O
New microbes and new infections, 07/2018, Letnik: 24Journal Article
Abstract Human coronaviruses (CoVs) are increasingly recognized as important respiratory pathogens associated with a broad range of clinical diseases. We sought to increase the insight into clinically relevant CoV infections by monitoring antigen concentrations in six confirmed CoV-positive patients using a newly developed assay for rapid detection of CoV OC43 infections. Antigen positivity lasted 3 to 6 days in secondary infections and 13 days in primary infection. CoV infections are clinically diverse, are common, and cannot be diagnosed from clinical symptoms alone.
