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Recenzirano
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Guan, Y.-F; Wu, C.-Y; Fang, Y.-Y; Zeng, Y.-N; Luo, Z.-Y; Li, S.-J; Li, X.-W; Zhu, X.-H; Mei, L; Gao, T.-M
Neuroscience, 10/2015, Letnik: 307Journal Article
Highlights • NRG1 protects against OGD-induced cortical neuronal apoptosis. • NRG1-mediated neuroprotection is blocked by neutralizing NRG1 and ErbB4 inhibition. • GABA receptor agonists have no synergistic effect with NRG1. • NRG1-mediated neuroprotection is partly blocked by GABA receptor antagonists. • The NRG1 neuroprotection against brain ischemia is abolished in PV-ErbB4−/− mice.
