Professor Zhang Fengchuan found from clinical observation that patients with vitiligo often had a variety of emotional abnormalities before the onset of disease, such as emotional depression, anxiety and panic, insomnia and dreaminess, anxiety and irritability, etc. ...it is believed that abnormal emotion and stagnation of liver qi are the main causes of vitiligo4 . (vi) Deficiency of liver and kidney, failure of nourishing skin and muscle. ...in case of deficiency of qi in the zang-fu organs and abnormality of zang-fu function, the qi and blood can not operate normally, resulting in failure to nourish the skin and muscle and developing into white patches. The first is latent onset and watching for the proper moment for action, namely toxins are accumulated in the body, which generally do not break out immediately, but will activate when the body is weak with declined immunity. Since qi, blood and body fluid are stagnated in the accumulation place of pathogenic toxin, and most of them are complex onsets of various pathogenic factors, the course of the disease is lingering and stubborn. According to modem medicine, stress, accumulation of toxic compounds , spread of infection, changes in cellular environment and impaired migration of melanocytes can lead to the occurrence of vitiligo7, and its pathogenesis is related