Depleted Monolithic Active Pixel Sensors (DMAPS) constitute a promising low cost alternative for the outer layers of the ATLAS experiment Inner Tracker (ITk). Realizations in modern, high resistivity CMOS technologies enhance their radiation tolerance by achieving substantial depletion of the sensing volume. Two DMAPS prototypes that use the same “column-drain” readout architecture and are based on different sensor implementation concepts named LF-Monopix and TJ-Monopix have been developed for the High Luminosity upgrade of the Large Hadron Collider (HL-LHC). LF-Monopix was fabricated in the LFoundry 150 nm technology and features pixel size of 50×250μm2 and large collection electrode opted for high radiation tolerance. Detection efficiency up to 99% has been measured after irradiation to 1⋅1015neq∕cm2. TJ-Monopix is a large scale (1×2cm2) prototype featuring pixels of 36×40μm2 size. It was fabricated in a novel TowerJazz 180 nm modified process that enables full depletion of the sensitive layer, while employing a small collection electrode that is less sensitive to crosstalk. The resulting small sensor capacitance (≤3 fF) is exploited by a compact, low power front end optimized to meet the 25 ns timing requirement. Measurement results demonstrate the sensor performance in terms of Equivalent Noise Charge (ENC) ≈11e−, threshold ≈300e−, threshold dispersion ≈30e− and total power consumption lower than 120 mW/cm2. •Depleted monolithic pixel sensors developed for the ATLAS ITk.•Different implemenation concepts featuring large and small collection electrodes.•Process modification to combine small capacitance with enhanced radiation tolerance.•Full functionality after irradiation.•High efficiency (LF-Monopix), High analog performance (TJ-Monopix).