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Chisiki, M; Kawada, A; Akiyama, M; Itoh, Y; Tajima, S; Ishibashi, A; Yudate, F
British journal of dermatology (1951), 19/May , Letnik: 140, Številka: 5Journal Article
Spontaneous regression is sometimes seen in malignant skin tumours. We report a 68‐year‐old woman whose Bowen's disease showed spontaneous complete regression. Prominent infiltration of T cells and increased vascularity were found in the upper dermis of the regressed lesion. Strong expression of Fas (APO‐1/CD95) antigen, an apoptosis‐related tumour necrosis factor receptor family protein, in the primary lesion and faint expression following regression suggest the involvement of Fas‐mediated apoptosis in the spontaneous complete regression of our patient's Bowen's disease.
