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  • Extramedullary Hematopoiesi...
    Dahlsgaard-Wallenius, Sara E.; Juul-Jensen, Karen; Nielsen, Anne Lerberg; Hildebrandt, Malene Grubbe

    Nuclear medicine and molecular imaging, 12/2022, Letnik: 56, Številka: 6
    Journal Article

    Beta-thalassemia is an inherited blood disorder caused by reduced or absent synthesis of the beta chains of hemoglobin, resulting in decreased hemoglobin production. Symptoms depend on the type of beta-thalassemia ranging from no symptoms to severe illness. Ineffective erythropoiesis leads to a sequence of events responsible for bone marrow expansion, anemia, hemolysis, splenomegaly, increased iron absorption, and sometimes extramedullary hematopoiesis (EMH). We report an interesting case with EMH visualized on FDG-PET/CT and where FDG-PET/CT has also found the focus of a severe infection in a patient with beta-thalassemia.