A new Dade Behring Cyclosporin A (CsA) assay has been made commercially accessible recently. The aim of this study was to examine the analytical performance of this assay and the correlation with the Abbott Diagnostics assay. The accuracy and precision within-run were good, but precision between-run slightly exceeded the manufacturer's recommendation on one quality-control material. Dade Behring CsA whole blood results from the kidney recipients (n = 104) were lower (p<0.001) than the Abbott results. The correlation between these two assays was significant (y = -15.61 + 0.751x; r= 0.974; p<0.001). Dade Behring CsA assay demonstrates adequate performance characteristics for routine clinical use and the main advantage is the full automatization without the need for samples pretreatment. Odnedavno je komercijalno dostupan novi Dade Behring test za odredivanje CsA u krvi. Naš cilj bio je da ispitamo analitičke karakteristike ovog testa i korelaciju sa Abbott Diagnostics testom. Tačnost i preciznost u seriji Dade Behring testa bili su zadovoljavajući, dok je preciznost iz dana u dan blago prevazilazila preporuku proizvodača u jednoj kontroli. Odredivanjem CsA u krvi pacijenata kojima je izvršena transplantacija bubrega (n=104) Dade Behring testom, dobijene su niže vrednosti (p<0,001) nego Abbott testom. Korelacija ove dve metode bila je statistički značajna (y = -15,61 + 0,751x; r = 0,974; p<0,001). Dade Behring test za odredivanje CsA pokazuje odgovarajuće karakteristike za rutinsku kliničku upotrebu, a glavna prednost je potpuna automatizacija testa bez potrebe za prethodnom pripremom uzorka.