The relatively new sea level satellite altimetry and secular coastal tide gauge data made the reconstruction of sea levels on regional and global scales possible about one century back. Due to better estimations of the Earth’s crustal, glacial, tectonic, and other possible motion biases in tide gauge data, some additional improvements can be expected in sea level reconstructions, analysis, and predictions. A more detailed review of published sea level-related results was conducted for the Eastern Adriatic coast, including the operation of the tide gauge network and data processing, crustal movement estimations, and the establishment of a new reference height system in Croatia, based on five tide gauge sea level data. It was shown that sea level variation and trend-related indicators are spatially homogeneous, especially on a sub-Adriatic scale. The regional Adriatic Sea mean sea level rise rate of +2.6 mm/year for the satellite altimetry era (1993–2019) is less than the global mean sea level (GMSL) rise rate of +3.3 mm/year for the period of 1993–2022. Several empirical methods for GMSL projections and expected IPCC (Intergovernmental Panel on Climate Change) assessments until the end of the 21st century are considered.