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Noack, F; Balleisen, L; Valent, P; Horny, H-P
Journal of clinical pathology, 10/2007, Letnik: 60, Številka: 10Journal Article
Immunohistochemical investigations revealed that neoplastic cells strongly expressed vimentin and CD31 ( fig 2 ), while expression of other endothelial-related markers like CD34 and FVIII-related antigen was much less intensive. ...the tumour cells were found to react strongly with antibodies against vascular endothelial growth factor (VEGF) and mast cell chymase ( fig 2 ). Expression of VEGF in angiosarcomas has been reported previously. 3 The strong expression of chymase-as in our case-has yet not been demonstrated in this tumour. ...we examined tissue samples from five archival cases of angiosarcoma and found expression of chymase in three of them.
