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  • Development of malignant ly...
    McCarthy, C. L.; Uchihara, Y.; Vlychou, M.; Grammatopoulos, G.; Athanasou, N. A.

    Skeletal radiology, 06/2017, Letnik: 46, Številka: 6
    Journal Article

    A number of previous studies have reported a potential risk of malignancy, particularly hematological malignancy, developing in patients receiving a metal-on-metal (MoM) hip replacement. We report a case of malignant lymphoma that arose in a patient who had an MoM hip arthroplasty complicated by development of a pseudotumour. The tumour was a B cell follicular lymphoma that involved lymph nodes and bone. Metal ions are known to have a genotoxic effect on lymphoid cells. Although epidemiological studies have not established that there is an increased risk of lymphoma associated with MoM implants, only a relatively short time period has elapsed since re-introduction of this type of implant and long-term follow-up of patients with MoM implants is indicated.